Article
Interleukin 6 (IL-6) and IL-10 Promoter Region Polymorphisms Are Associated with Risk of Lumbar Disc Herniation in a Northern Chinese Han Population.
Genetic testing and molecular biomarkers - 1 Jan 2017
Huang Xiangye, Chen Feng, Zhao Jing, Wang Dezhang, Jing Shenfeng, Li Hongmei, Meng Chunyang
Abstract excerpt
AIM: This study assessed the association of single-nucleotide polymorphisms (SNPs) in the proinflammatory cytokines interleukin 6 (IL-6) and IL-10 with the risk of lumbar disc herniation in a Chinese Han population. METHODS: We collected blood samples from 267 patients with lumbar disc herniation (case group) and 300 normals (control group) and performed analyses of the IL-6 572C/G and 174G/C SNPs as well as the...
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