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Article

An intron SNP rs2069837 in IL-6 is associated with osteonecrosis of the femoral head development.

BMC medical genomics - 5 Jan 2022

Wang Ruisong, Li Rui, Liu Ruiyu

Abstract excerpt

BACKGROUND: Genetic polymorphisms play a crucial role in the development of osteonecrosis of the femoral head (ONFH). This study mainly explored the association of IL-6 variants and ONFH susceptibility among the Chinese Han population. METHODS: Two variants (rs2069837, and rs13306435) in the IL-6 gene were identified and genotyped from 566 patients with ONFH and 566 healthy controls. The associations between IL-6...

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Identifiers

PMID: 34986839
DOI: 10.1186/s12920-021-01142-3
PMCID: PMC8734317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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