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Article

Serotonergic modulation of 'waiting impulsivity' is mediated by the impulsivity phenotype in humans.

Translational psychiatry - 8 Nov 2016

Neufang S, Akhrif A, Herrmann C G, Drepper C, Homola G A, Nowak J, Waider J, Schmitt A G, Lesch K-P, Romanos M

Abstract excerpt

In rodents, the five-choice serial reaction time task (5-CSRTT) has been established as a reliable measure of waiting impulsivity being defined as the ability to regulate a response in anticipation of reinforcement. Key brain structures are the nucleus accumbens (NAcc) and prefrontal regions (for example, pre- and infralimbic cortex), which are, together with other transmitters, modulated by serotonin. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27824354
DOI: 10.1038/tp.2016.210
PMCID: PMC5314122

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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