Psychological, Neuroimaging, and Biochemical Studies on Functional Association between Impulsive Behavior and the 5‐HT_2A Receptor Gene Polymorphism in Humans

Abstract excerpt

It has been suggested that impulsive behavior is caused by dysfunctional serotonergic 5-HT neurotransmission in the central nervous system (CNS). Brain neuroimaging studies have shown that behavioral inhibition is linked to the activation of cortex sites such as the ventral frontal cortex. Positron emission tomography (PET) imaging with [(18)F]altanserin to characterize 5-HT(2A) receptor binding revealed a...

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