Article
Genotype Analyses in the Japanese and Belarusian Populations Reveal Independent Effects of rs965513 and rs1867277 but Do Not Support the Role of FOXE1 Polyalanine Tract Length in Conferring Risk for Papillary Thyroid Carcinoma.
Thyroid : official journal of the American Thyroid Association - 1 Feb 2017
Nikitski Alyaksandr V, Rogounovitch Tatiana I, Bychkov Andrey, Takahashi Meiko, Yoshiura Koh-Ichiro, Mitsutake Norisato, Kawaguchi Takahisa, Matsuse Michiko, Drozd Valentina M, Demidchik Yuri, Nishihara Eijun, Hirokawa Mitsuyoshi, Miyauchi Akira, Rubanovich Alexander V, Matsuda Fumihiko, Yamashita Shunichi, Saenko Vladimir A
Abstract excerpt
BACKGROUND: Several functional single-nucleotide polymorphisms (SNPs) at the FOXE1 locus on chromosome 9q22.33 have been associated with the risk for papillary thyroid carcinoma (PTC). This study set out to elucidate whether their effects are independent, using genotyping results in populations of Asian and European descent. METHODS: SNPs rs965513 and rs1867277 and a polymorphic region determining the length of...
Read the complete abstract on PubMed