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Article

The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.

Human molecular genetics - 15 Jun 2010

Takahashi Meiko, Saenko Vladimir A, Rogounovitch Tatiana I, Kawaguchi Takahisa, Drozd Valentina M, Takigawa-Imamura Hisako, Akulevich Natallia M, Ratanajaraya Chanavee, Mitsutake Norisato, Takamura Noboru, Danilova Larisa I, Lushchik Maxim L, Demidchik Yuri E, Heath Simon, Yamada Ryo, Lathrop Mark, Matsuda Fumihiko, Yamashita Shunichi

Abstract excerpt

Papillary thyroid cancer (PTC) among individuals exposed to radioactive iodine in their childhood or adolescence is a major internationally recognized health consequence of the Chernobyl accident. To identify genetic determinants affecting individual susceptibility to radiation-related PTC, we conducted a genome-wide association study employing Belarusian patients with PTC aged 0-18 years at the time of accident...

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Share to Carcinoma, Papillary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20350937
DOI: 10.1093/hmg/ddq123

Genes

FOXE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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