Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of FOXE1 polyalanine repeat region with papillary thyroid cancer.

The Journal of clinical endocrinology and metabolism - 1 Sept 2012

Bullock Martyn, Duncan Emma L, O'Neill Christine, Tacon Lyndal, Sywak Mark, Sidhu Stan, Delbridge Leigh, Learoyd Diana, Robinson Bruce G, Ludgate Marian, Clifton-Bligh Roderick J

Abstract excerpt

CONTEXT: Polyalanine tract variations in transcription factors have been identified for a wide spectrum of developmental disorders. The thyroid transcription factor forkhead factor E1 (FOXE1) contains a polymorphic polyalanine tract with 12-22 alanines. Single-nucleotide polymorphisms (SNP) close to this locus are associated with papillary thyroid cancer (PTC), and a strong linkage disequilibrium block extends...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Papillary
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Forkhead Transcription Factors

Share to HEK293 Cells

Share to Peptides

Share to Repetitive Sequences, Nucleic Acid

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 22736773
DOI: 10.1210/jc.2012-1456

Genes

FOXE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of FOXE1 polyalanine repeat region with papillary thyroid cancer.PMID 22736773Read ↗

Genotype Analyses in the Japanese and Belarusian Populations Reveal Independent Effects of rs965513 and rs1867277 but Do Not Support the Role of FOXE1 Polyalanine Tract Length in Conferring Risk for Papillary Thyroid Carcinoma.Semantic proximity Read ↗

Association of FOXE1 polyalanine repeat region with thyroid cancer is dependent on tumour size.Semantic proximity Read ↗

Genetic investigation of FOXE1 polyalanine tract in thyroid diseases: new insight on the role of FOXE1 in thyroid carcinoma.Semantic proximity Read ↗

Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer.Semantic proximity Read ↗

FOXE1 polyalanine tract length polymorphism in patients with thyroid hemiagenesis and subjects with normal thyroid.Semantic proximity Read ↗

Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR, and a novel lincRNA gene, PTCSC2.Semantic proximity Read ↗

Characterizing the function of EPB41L4A in the predisposition to papillary thyroid carcinoma.Semantic proximity Read ↗

Common genetic variants on FOXE1 contributes to thyroid cancer susceptibility: evidence based on 16 studies.Semantic proximity Read ↗

Somatic Mutations of FOXE1 in Papillary Thyroid Cancer.Semantic proximity Read ↗

Genetic predisposition to papillary thyroid carcinoma is mediated by a long non-coding RNA TINCR enhancer polymorphism.Semantic proximity Read ↗

Polymorphic length of FOXE1 alanine stretch: evidence for genetic susceptibility to thyroid dysgenesis.Semantic proximity Read ↗

The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.