Article
Age at diagnosis and gender modify the risk of 9q22 and 14q13 polymorphisms for papillary thyroid carcinoma.
Endokrynologia Polska - 1 Jan 2017
Kula Dorota, Kalemba Michał, Puch Zbigniew, Polańska Joanna, Świerniak Michał, Rusinek Dagmara, Żebracka-Gala Jadwiga, Kowalska Małgorzata, Handkiewicz-Junak Daria, Kowal Monika, Tyszkiewicz Tomasz, Piasna Ewelina, Czarniecka Agnieszka, Pawlaczek Agnieszka, Krajewska Jolanta, Szpak-Ulczok Sylwia, Jarząb Barbara
Abstract excerpt
INTRODUCTION: Papillary thyroid cancer (PTC) shows familial occurrence, and some susceptibility single nucleotide polymorphisms (SNPs) have been identified in FOXE1 and near the NKX2-1 locus. The aim of our study was to analyse the association of PTC risk with SNPs in FOXE1 (rs965513, rs1867277, rs1443434) and near the NKX2-1 locus (rs944289) in a Polish population, and, in the second step, the interac-tion...
