Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer.

doi:10.1073/pnas.1506255112

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Article

Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer.

Proceedings of the National Academy of Sciences of the United States of America - 12 May 2015

He Huiling, Li Wei, Liyanarachchi Sandya, Srinivas Mukund, Wang Yanqiang, Akagi Keiko, Wang Yao, Wu Dayong, Wang Qianben, Jin Victor, Symer David E, Shen Rulong, Phay John, Nagy Rebecca, de la Chapelle Albert

Abstract excerpt

The [A] allele of SNP rs965513 in 9q22 has been consistently shown to be highly associated with increased papillary thyroid cancer (PTC) risk with an odds ratio of ∼1.8 as determined by genome-wide association studies, yet the molecular mechanisms remain poorly understood. Previously, we noted th...

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Identifiers

PMID: 25918370
DOI: 10.1073/pnas.1506255112
PMCID: PMC4434723

Genes

FOXE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25918370-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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