Article
Genetic investigation of FOXE1 polyalanine tract in thyroid diseases: new insight on the role of FOXE1 in thyroid carcinoma.
Cancer biomarkers : section A of Disease markers - 1 Jan 2010
Kallel Rihab, Belguith-Maalej Salima, Akdi Abdelmounaim, Mnif Mouna, Charfeddine Ilhem, Galofré Pere, Ghorbel Abdelmonaim, Abid Mohamed, Marcos Ricard, Ayadi Hammadi, Velázquez Antonia, Hadj Kacem Hassen
Abstract excerpt
FOXE1 polyalanine tract (poly-Ala) has been associated with thyroid dysgenesis. Recently, the SNP (rs1867277:-238G>A) within the FOXE1 5'UTR was involved in the genetic susceptibility to thyroid cancer (TC). In the aim to assess the influence of FOXE1 poly-Ala length on the genetic susceptibility to TC and autoimmune thyroid diseases (AITD), a case-control design (including 261 Tunisian AITD, 170 Spanish TC and...
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