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Article

Nesfatin-1 promotes brown adipocyte phenotype.

Scientific reports - 8 Nov 2016

Wang Yuexin, Li Ziru, Zhang Xinyu, Xiang Xinxin, Li Yin, Mulholland Michael W, Zhang Weizhen

Abstract excerpt

Nesfatin-1, an 82 amino acid gastric peptide, is involved in regulation of food uptake and in multiple metabolic activities. Whether nesfatin-1 modulates the differentiation and lipid metabolism of brown adipocytes remains unknown. In the present study, we found that nesfatin-1 mRNA and protein were detectable in isolated brown adipocytes and gradually decreased during differentiation (95% CI 0.6057 to 1.034,...

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Identifiers

PMID: 27824141
DOI: 10.1038/srep34747
PMCID: PMC5099693

Genes

UCP1
TSC1
PRDM16
UCP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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