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Article

A systems perspective on brown adipogenesis and metabolic activation

1 Feb 2017

Abstract excerpt

Brown adipocytes regulate energy expenditure via mitochondrial uncoupling. This makes these fat cells attractive therapeutic targets to tackle the burgeoning issue of obesity, which itself is coupled to insulin resistance, type 2 diabetes, cardiovascular and fatty liver disease. Recent research has revealed a complex network underlying brown fat cell differentiation and thermogenic activation, involving secreted...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 28164456
DOI: 10.1111/obr.12512

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