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Article

MicroRNA-26 Family Is Required for Human Adipogenesis and Drives Characteristics of Brown Adipocytes

3 Dec 2013

Abstract excerpt

Adipose tissue contains thermogenic adipocytes (i.e., brown and brite/beige) that oxidize nutrients at exceptionally high rates via nonshivering thermogenesis. Its recent discovery in adult humans has opened up new avenues to fight obesity and related disorders such as diabetes. Here, we identified miR-26a and -26b as key regulators of human white and brite adipocyte differentiation. Both microRNAs are...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 24375761
DOI: 10.1002/stem.1603

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