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Article

A phylogenetic method to perform genome-wide association studies in microbes that accounts for population structure and recombination.

PLoS computational biology - 1 Feb 2018

Collins Caitlin, Didelot Xavier

Abstract excerpt

Genome-Wide Association Studies (GWAS) in microbial organisms have the potential to vastly improve the way we understand, manage, and treat infectious diseases. Yet, microbial GWAS methods established thus far remain insufficiently able to capitalise on the growing wealth of bacterial and viral genetic sequence data. Facing clonal population structure and homologous recombination, existing GWAS methods struggle...

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Identifiers

PMID: 29401456
DOI: 10.1371/journal.pcbi.1005958
PMCID: PMC5814097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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