Article
Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability.
Proceedings of the National Academy of Sciences of the United States of America - 22 Nov 2016
Buhl Edgar, Bradlaugh Adam, Ogueta Maite, Chen Ko-Fan, Stanewsky Ralf, Hodge James J L
Abstract excerpt
We have characterized a light-input pathway regulating Drosophila clock neuron excitability. The molecular clock drives rhythmic electrical excitability of clock neurons, and we show that the recently discovered light-input factor Quasimodo (Qsm) regulates this variation, presumably via an Na+, K+, Cl- cotransporter (NKCC) and the Shaw K+ channel (dKV3.1). Because of light-dependent degradation of the clock...
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