Article
A new statistical framework for genetic pleiotropic analysis of high dimensional phenotype data.
BMC genomics - 7 Nov 2016
Wang Panpan, Rahman Mohammad, Jin Li, Xiong Momiao
Abstract excerpt
BACKGROUND: The widely used genetic pleiotropic analyses of multiple phenotypes are often designed for examining the relationship between common variants and a few phenotypes. They are not suited for both high dimensional phenotypes and high dimensional genotype (next-generation sequencing) data. To overcome limitations of the traditional genetic pleiotropic analysis of multiple phenotypes, we develop sparse...
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