Article
Heterologous expression of the Crassostrea gigas (Pacific oyster) alternative oxidase in the yeast Saccharomyces cerevisiae.
Journal of bioenergetics and biomembranes - 1 Oct 2016
Robertson Aaron, Schaltz Kyle, Neimanis Karina, Staples James F, McDonald Allison E
Abstract excerpt
Alternative oxidase (AOX) is a terminal oxidase within the inner mitochondrial membrane (IMM) present in many organisms where it functions in the electron transport system (ETS). AOX directly accepts electrons from ubiquinol and is therefore capable of bypassing ETS Complexes III and IV. The human genome does not contain a gene coding for AOX, so AOX expression has been suggested as a gene therapy for a range of...
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