Article
Structure models of G72, the product of a susceptibility gene to schizophrenia.
Journal of biochemistry - 1 Feb 2017
Kato Yusuke, Fukui Kiyoshi
Abstract excerpt
The G72 gene is one of the most susceptible genes to schizophrenia and is contained exclusively in the genomes of primates. The product of the G72 gene modulates the activity of D-amino acid oxidase (DAO) and is a small protein prone to aggregate, which hampers its structural studies. In addition, lack of a known structure of a homologue makes it difficult to use the homology modelling method for the prediction...
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