Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Computer construction and analysis of protein models of the mutant gammaD-crystallin gene.

Chinese medical journal - 5 May 2005

Yao Ke, Sun Zhao-hui, Shentu Xing-chao, Wang Kai-jun, Tan Jian

Abstract excerpt

BACKGROUND: Gammad-crystallin plays an important role in human cataract formation. Being highly stable, gammaD-crystallin proteins are composed of two domains. In this study we constructed and analyzed protein models of the mutant gammaD-crystallin gene, which caused a special fasciculiform congenital cataract affecting a large Chinese family. METHODS: gammaD-crystallin protein structure was predicted by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Computer Simulation
Share to gamma-Crystallins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen Bonding

Share to Models, Molecular

Share to Mutation

Share to Protein Structure, Tertiary

Source

Identifiers

PMID: 15899135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Computer construction and analysis of protein models of the mutant gammaD-crystallin gene.PMID 15899135Read ↗

Prediction of stability factors at the domain interface of human gammaB crystallin maintaining the transparency of the eye lens.Semantic proximity Read ↗

[Comparison on molecular characteristics of human gamma D-crystallin protein and its five mutations].Semantic proximity Read ↗

[Ultrastructure and crystallin mutant molecular modeling of hereditary coralliform cataract].Semantic proximity Read ↗

The importance of the fourth Greek key motif of human γD-crystallin in maintaining lens transparency-the tale told by the tail.Semantic proximity Read ↗

Conformational change and destabilization of cataract gammaC-crystallin T5P mutant.Semantic proximity Read ↗

Cataract-associated New Mutants S175G/H181Q of βB2-Crystallin and P24S/S31G of γD-Crystallin are Involved in Protein aggregation by Structural ChangesSemantic proximity Read ↗

Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state.Semantic proximity Read ↗

A novel gammaD-crystallin mutation causes mild changes in protein properties but leads to congenital coralliform cataract.Semantic proximity Read ↗

Progressive juvenile-onset punctate cataracts caused by mutation of the gammaD-crystallin gene.Semantic proximity Read ↗

[Computer construction and analysis of protein models of mutant fibrillin-1 gene in Marfan's syndrome].Semantic proximity Read ↗

Cataract-Associated New Mutants S175G/H181Q of βΒ2-Crystallin and P24S/S31G of γD-Crystallin Are Involved in Protein Aggregation by Structural Changes.Semantic proximity Read ↗

Link between a novel human gammaD-crystallin allele and a unique cataract phenotype explained by protein crystallography.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.