Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacoinformatics, Adaptive Evolution, and Elucidation of Six Novel Compounds for Schizophrenia Treatment by Targeting DAOA (G72) Isoforms.

BioMed research international - 1 Jan 2017

Sehgal Sheikh Arslan

Abstract excerpt

Studies on Schizophrenia so far reveal a complex picture of neurological malfunctioning reported to be strongly associated with DAOA. Detailed sequence analyses proved DAOA as a primate specific gene having conserved gene desert region on both upstream and downstream region. The analyses of 10 MB chromosomal region of primates, birds, rodents, and reptiles having DAOA evidenced the conserved part in primates and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Docking Simulation

Share to Protein Interaction Maps

Share to Protein Isoforms

Share to Schizophrenia

Share to Small Molecule Libraries

Share to User-Computer Interface

Source

Open in PubMed Open full text

Identifiers

PMID: 28197415
DOI: 10.1155/2017/5925714
PMCID: PMC5288522

Genes

DAOA
DAO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacoinformatics, Adaptive Evolution, and Elucidation of Six Novel Compounds for Schizophrenia Treatment by Targeting DAOA (G72) Isoforms.PMID 28197415Read ↗

PhenoPredict: A disease phenome-wide drug repositioning approach towards schizophrenia drug discovery.Semantic proximity Read ↗

[Approach for identifying novel drug targets of schizophrenia].Semantic proximity Read ↗

Uncovering novel therapeutics for schizophrenia: a multitarget approach using the CANDO platformSemantic proximity Read ↗

G72 primate-specific gene: a still enigmatic element in psychiatric disorders.Semantic proximity Read ↗

The C-terminal region of G72 increases D-amino acid oxidase activity.Semantic proximity Read ↗

Association of DAOA polymorphisms with schizophrenia and clinical symptoms or therapeutic effects.Semantic proximity Read ↗

Bioavailability and Neuroprotectivity of 3-(3, 4-dimethoxy phenyl)-1-4 (methoxy phenyl) prop-2-en-1-one against Schizophrenia: an in silico approach.Semantic proximity Read ↗

Association between the DAOA/G72 gene and bipolar disorder and meta-analyses in bipolar disorder and schizophrenia.Semantic proximity Read ↗

Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample.Semantic proximity Read ↗

Adenosine Hypothesis of Antipsychotic Drugs Revisited: Pharmacogenomics Variation in Nonacute Schizophrenia.Semantic proximity Read ↗

The DAOA gene is associated with schizophrenia in the Taiwanese population.Semantic proximity Read ↗

Combination of G72 Genetic Variation and G72 Protein Level to Detect Schizophrenia: Machine Learning ApproachesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.