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Article

Methodologic Considerations in the Application of Next-Generation Sequencing of Human TRB Repertoires for Clinical Use.

The Journal of molecular diagnostics : JMD - 1 Jan 2017

Xu Liwen, You Xiaoqing, Zheng PingPing, Zhang Bing M, Gupta Puja K, Lavori Philip, Meyer Everett, Zehnder James L

Abstract excerpt

Next-generation sequencing (NGS) of immune receptors has become a standard tool to assess minimal residual disease (MRD) in patients treated for lymphoid malignancy, and it is being used to study the T-cell repertoire in many clinical settings. To better understanding the potential clinical utility and limitations of this application outside of MRD, we developed a BIOMED-2 primer-based NGS method and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27815002
DOI: 10.1016/j.jmoldx.2016.07.009
PMCID: PMC5225307

Genes

TRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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