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Article

Next generation sequencing: new tools in immunology and hematology

1 Jan 2013

Abstract excerpt

One of the hallmarks of the adaptive immune system is the specificity of B and T cell receptors. Thanks to somatic recombination, a large repertoire of receptors can be generated within an individual that guarantee the recognition of a vast number of antigens. Monoclonal antibodies have limited applicability, given the high degree of diversity among these receptors, in BCR and TCR monitoring. Furthermore, with...

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PMID: 24466547
DOI: 10.5045/br.2013.48.4.242

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