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Article

The CEA-/lo colorectal cancer cell population harbors cancer stem cells and metastatic cells.

Oncotarget - 6 Dec 2016

Yan Chang, Hu Yibing, Zhang Bo, Mu Lei, Huang Kaiyu, Zhao Hui, Ma Chensen, Li Xiaolan, Tao Deding, Gong Jianping, Qin Jichao

Abstract excerpt

Serum carcinoembryonic antigen (CEA) is the most commonly used tumor marker in a variety of cancers including colorectal cancer (CRC) for tumor diagnosis and monitoring. Recent studies have shown that colonic crypt cells expressing little or no CEA may enrich for stem cells. Numerous studies have clearly shown that there exist CRC patients with normal serum CEA levels during tumor progression or even tumor...

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Identifiers

PMID: 27813496
DOI: 10.18632/oncotarget.13029
PMCID: PMC5348349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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