Article
The Role of Colorectal Cancer Stem Cells in Metastatic Disease and Therapeutic Response
14 Jan 2011
Abstract excerpt
Colorectal cancer is the third-leading cause of cancer related mortality in the United States. The intricate molecular mechanisms involved in the regenerative process of the normal intestine and the identity of putative somatic intestinal stem cells have become clear. In parallel with this, experiment evidence has emerged supporting the century old hypothesis that solid tumor initiation, progression,...
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