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Article

How the interplay among the tumor microenvironment and the gut microbiota influences the stemness of colorectal cancer cells

25 May 2023

Abstract excerpt

Colorectal cancer (CRC) remains the third most prevalent cancer disease and involves a multi-step process in which intestinal cells acquire malignant characteristics. It is well established that the appearance of distal metastasis in CRC patients is the cause of a poor prognosis and treatment failure. Nevertheless, in the last decades, CRC aggressiveness and progression have been attributed to a specific cell...

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PMID: 37342226
DOI: 10.4252/wjsc.v15.i5.281

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