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Detecting the Senescence-Associated Secretory Phenotype (SASP) by High Content Microscopy Analysis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Hari Priya, Acosta Juan Carlos

Abstract excerpt

The diverse arrays of proteins secreted by senescent cells have been described to influence aging and to have both pro-tumorigenic and anti-tumorigenic influences on the surrounding microenvironment. Further characterization of these proteins, known as the senescence-associated secretory phenotype (SASP), and their regulators is required to understand and further manipulate such activities. The use of...

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PMID: 27812871
DOI: 10.1007/978-1-4939-6670-7_9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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