Article
IL-10 and PRKDC polymorphisms are associated with glioma patient survival.
Oncotarget - 6 Dec 2016
Hu Mingjun, Du Jieli, Cui Lihong, Huang Tingqin, Guo Xiaoye, Zhao Yonglin, Ma Xudong, Jin Tianbo, Li Gang, Song Jinning
Abstract excerpt
Interleukin-10 (IL-10) and DNA repair gene PRKDC mutations are implicated in the development of multiple human cancers, including glioma. We investigated associations between IL-10 and PRKDC gene polymorphisms and prognosis in low- and high-grade glioma patients. We analyzed the associations of one IL-10 and one PRKDC single nucleotide polymorphism with patient clinical factors in 481 glioma patients using Cox...
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