Article
Psoriasis risk SNPs and their association with HIV-1 control.
Human immunology - 1 Feb 2017
Nititham Joanne, Gupta Rashmi, Zeng Xue, Hartogensis Wendy, Nixon Douglas F, Deeks Steven G, Hecht Frederick M, Liao Wilson
Abstract excerpt
Human evolution has resulted in selection for genetic polymorphisms beneficial in the defense against pathogens. However, such polymorphisms may have the potential to heighten the risk of autoimmune disease. Here, we investigated whether psoriasis-associated single nucleotide polymorphisms influence host control of HIV-1 infection. We studied psoriasis and viral immune response variants in three HIV-positive...
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