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Article

Biology of double-hit B-cell lymphomas

13 Apr 2012

Abstract excerpt

PURPOSE OF REVIEW: Mature B-cell lymphomas bearing concurrent chromosomal rearrangement of MYC/8q24 and BCL2/18q21 are associated with an aggressive clinical course and resistance to conventional chemotherapy. This review summarizes the recent literature regarding the clinical and pathologic features of double-hit lymphomas and outlines current questions about the most accurate and inclusive definition of the...

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PMID: 22504522
DOI: 10.1097/moh.0b013e328353bbbd

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