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The expression pattern of matrix-producing tumor stroma is of prognostic importance in breast cancer

3 Nov 2016

Abstract excerpt

BACKGROUND: There are several indications that the composition of the tumor stroma can contribute to the malignancy of a tumor. Here we utilized expression data sets to identify metagenes that may serve as surrogate marker for the extent of matrix production and vascularization of a tumor and to characterize prognostic molecular components of the stroma. METHODS: TCGA data sets from six cancer forms, two breast...

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PMID: 27809802
DOI: 10.1186/s12885-016-2864-2

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