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Article

A clinically relevant gene signature in triple negative and basal-like breast cancer

6 Oct 2011

Abstract excerpt

INTRODUCTION: Current prognostic gene expression profiles for breast cancer mainly reflect proliferation status and are most useful in ER-positive cancers. Triple negative breast cancers (TNBC) are clinically heterogeneous and prognostic markers and biology-based therapies are needed to better treat this disease. METHODS: We assembled Affymetrix gene expression data for 579 TNBC and performed unsupervised...

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PMID: 21978456
DOI: 10.1186/bcr3035

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