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Article

FREM1 Serves as a Novel Therapeutic Target in Breast Cancer through Basement Membrane-Based Prognostic Modeling with Integrated Bioinformatics and Experimental Validation

2025-08-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background​​</bold>: Breast cancer remains the leading cause of cancer-related mortality in women worldwide, with metastatic disease posing significant therapeutic challenges. While immunotherapy has shown promise, tumor immune evasion limits its efficacy. The basement membrane (BM), a specialized extracellular matrix structure, plays a crucial yet understudied role in breast canc...

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Literature Corpus work
6c4372f5-b2f8-5ca8-9174-bd6d9c5ff853
DOI
10.21203/rs.3.rs-7206387/v1
Open publication

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FREM1 Serves as a Novel Therapeutic Target in Breast Cancer through Basement Membrane-Based Prognostic Modeling with Integrated Bioinformatics and Experimental ValidationDOI 10.21203/rs.3.rs-7206387/v1
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