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Article

Kmt2acooperates with menin to suppress tumorigenesis in mouse pancreatic islets

1 Nov 2016

Abstract excerpt

The reported incidence of pancreatic neuroendocrine tumors (PanNETs) has increased, due in large part to improvements in detection and awareness. However, therapeutic options are limited and a critical need exists for understanding a more thorough characterization of the molecular pathology underlying this disease. The Men1 knockout mouse model recapitulates the early stage of human PanNET development and can...

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Identifiers

PMID: 27801610
DOI: 10.1080/15384047.2016.1250986

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