Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apoptotic endonuclease EndoG regulates alternative splicing of human telomerase catalytic subunit hTERT

1 Jan 2016

Abstract excerpt

Human telomerase catalytic subunit hTERT is subjected to alternative splicing results in loss of its function and leads to decrease of telomerase activity. However, very little is known about the mechanism of hTERT pre-mRNA alternative splicing. Apoptotic endonuclease EndoG is known to participate this process. The aim of this study was to determine the role of EndoG in regulation of hTERT alternative splicing....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA Interference and Gene Delivery
Share to RNA regulation and disease
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27797329
DOI: 10.18097/pbmc20166205544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apoptotic endonuclease EndoG regulates alternative splicing of human telomerase catalytic subunit hTERTPMID 27797329Read ↗

Apoptotic endonuclease EndoG induces alternative splicing of telomerase catalytic subunit hTERT and death of tumor cellsSemantic proximity Read ↗

Apoptotic endonuclease EndoG inhibits telomerase activity and induces malignant transformation of human CD4+ T cellsSemantic proximity Read ↗

Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity.Semantic proximity Read ↗

Alternative Splicing of Human Telomerase Reverse Transcriptase (hTERT) and Its Implications in Physiological and Pathological ProcessesSemantic proximity Read ↗

Regulation of Telomerase Alternative Splicing: A Target for ChemotherapySemantic proximity Read ↗

Conservation of the pro-apoptotic nuclease activity of endonuclease G in unicellular trypanosomatid parasitesSemantic proximity Read ↗

Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stabilitySemantic proximity Read ↗

Exclusion of Exon 2 Is a Common mRNA Splice Variant of Primate Telomerase Reverse TranscriptasesSemantic proximity Read ↗

p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis.Semantic proximity Read ↗

Expression Profile of a γ-Deletion Variant of the Human Telomerase Reverse Transcriptase GeneSemantic proximity Read ↗

Effect of antisense human telomerase RNA on malignant phenotypes of gastric carcinoma.Semantic proximity Read ↗

Complicated RNA splicing of chicken telomerase reverse transcriptase revealed by profiling cells both positive and negative for telomerase activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.