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Article

Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity.

International journal of molecular sciences - 7 Mar 2017

Liu Xuewen, Wang Yuchuan, Chang Guangming, Wang Feng, Wang Fei, Geng Xin

Abstract excerpt

The activation of telomerase is one of the key events in the malignant transition of cells, and the expression of human telomerase reverse transcriptase (hTERT) is indispensable in the process of activating telomerase. The pre-mRNA alternative splicing of hTERT at the post-transcriptional level is one of the mechanisms for the regulation of telomerase activity. Shifts in splicing patterns occur in the...

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Identifiers

PMID: 28272339
DOI: 10.3390/ijms18030567
PMCID: PMC5372583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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