A Neuroprotective Effect of the Glutamate Receptor Antagonist MK801 on Long-Term Cognitive and Behavioral Outcomes Secondary to Experimental Cerebral Malaria.

doi:10.1007/s12035-016-0226-3

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Article

A Neuroprotective Effect of the Glutamate Receptor Antagonist MK801 on Long-Term Cognitive and Behavioral Outcomes Secondary to Experimental Cerebral Malaria.

Molecular neurobiology - 1 Nov 2017

de Miranda Aline Silva, Brant Fátima, Vieira Luciene Bruno, Rocha Natália Pessoa, Vieira Érica Leandro Marciano, Rezende Gustavo Henrique Souza, de Oliveira Pimentel Pollyana Maria, Moraes Marcio F D, Ribeiro Fabíola Mara, Ransohoff Richard M, Teixeira Mauro Martins, Machado Fabiana Simão, Rachid Milene Alvarenga, Teixeira Antônio Lúcio

Abstract excerpt

Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum infection, which can result in long-term cognitive and behavioral deficits despite successful anti-malarial therapy. Due to the substantial social and economic burden of CM, the development of adjuvant therapies is a scientific goal of highest priority. Apart from vascular and immune responses, changes in glutamate system have been...

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PMID: 27796746
DOI: 10.1007/s12035-016-0226-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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