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Article

The HFE genotype and a formulated diet controlling for iron status attenuate experimental cerebral malaria in mice.

International journal for parasitology - 1 Oct 2015

Leitner Dominique F, Stoute José A, Landmesser Mary, Neely Elizabeth, Connor James R

Abstract excerpt

Plasmodium falciparum infects approximately 500million individuals each year. A small but significant number of infections lead to complications such as cerebral malaria. Cerebral malaria is associated with myelin damage and neurological deficits in survivors, and iron status is thought to impact the outcome of infection. We evaluated whether a mouse model of experimental cerebral malaria with Plasmodium berghei...

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Source

Identifiers

PMID: 26296689
DOI: 10.1016/j.ijpara.2015.07.003

Genes

HFE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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