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Article

Importance of Highly Conserved Peptide Sites of Human Cytomegalovirus gO for Formation of the gH/gL/gO Complex.

Journal of virology - 1 Jan 2017

Stegmann Cora, Abdellatif Mohamed E A, Laib Sampaio Kerstin, Walther Paul, Sinzger Christian

Abstract excerpt

The glycoprotein O (gO) is betaherpesvirus specific. Together with the viral glycoproteins H and L, gO forms a covalent trimeric complex that is part of the viral envelope. This trimer is crucial for cell-free infectivity of human cytomegalovirus (HCMV) but dispensable for cell-associated spread. We hypothesized that the amino acids that are conserved among gOs of different cytomegaloviruses are important for the...

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Identifiers

PMID: 27795411
DOI: 10.1128/JVI.01339-16
PMCID: PMC5165187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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