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Article

Inflammatory phenotype drives different immunosuppressive response in COPD exacerbations.

BMC pulmonary medicine - 14 Feb 2026

Miralles Cristina, Miñana María Dolores, Nieto María Luisa, Del Carmen Aguar María, Domínguez-Márquez Victoria, Soler-Cataluña Juan José

Abstract excerpt

BACKGROUND: COPD is heterogeneous, with immunosuppression contributing to immune dysfunction. We hypothesized that the immunosuppressive response varies by inflammatory phenotype during both stable disease (SCOPD) and acute exacerbations (AECOPD). METHODS: COPD patients were monitored during AECOPD hospitalization and subsequent clinical stability. Serum key pro- and anti-inflammatory molecules were measured....

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Identifiers

PMID: 41691196
DOI: 10.1186/s12890-025-04020-1
PMCID: PMC12918604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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