Article
"Frequent exacerbator" is a phenotype of poor prognosis in Japanese patients with chronic obstructive pulmonary disease.
International journal of chronic obstructive pulmonary disease - 1 Jan 2016
Tomioka Ryusuke, Kawayama Tomotaka, Suetomo Masashi, Kinoshita Takashi, Tokunaga Yoshihisa, Imaoka Haruki, Matsunaga Kazuko, Okamoto Masaki, Hoshino Tomoaki
Abstract excerpt
BACKGROUND: The prognosis of Japanese patients with COPD who suffer repeated exacerbations is unclear, although Westerners with such episodes have a poor prognosis. MATERIALS AND METHODS: We conducted a 1-year prospective observational trial involving 90 Japanese patients with COPD: 58 nonexacerbators, 12 infrequent exacerbators, and 20 frequent exacerbators classified on the basis of exacerbation frequency...
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