Article
Efficacy of roflumilast in the COPD frequent exacerbator phenotype.
Chest - 1 May 2013
Wedzicha Jadwiga A, Rabe Klaus F, Martinez Fernando J, Bredenbröker Dirk, Brose Manja, Goehring Udo-Michael, Calverley Peter M A
Abstract excerpt
BACKGROUND: COPD exacerbations are associated with increased morbidity and mortality and can accelerate disease progression. The best predictor of future exacerbations is a history of previous exacerbations, which helps identify a frequent exacerbator phenotype. This post hoc analysis evaluated the effect of roflumilast, a drug known to reduce the COPD exacerbation rate, on exacerbation status. METHODS: Pooled...
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