The frequent exacerbator phenotype in bronchiectasis revisited: data from EMBARC registry.

doi:10.1093/ajrccm/aamag297

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Article

The frequent exacerbator phenotype in bronchiectasis revisited: data from EMBARC registry.

American journal of respiratory and critical care medicine - 1 Sept 2026

Sibila Oriol, Perea Lidia, Burgel Pierre Regis, Polverino Eva, Hull Rebecca C, Long Merete B, Chotirmall Sanjay H, Shteinberg Michal, Pollock Jennifer, Stobo Jamie, Lind Holly, Haworth Charles, Dimakou Katerina, Bossios Apostolos, Loebinger Michael R, Dhar Raja, Xu Jin-Fu, Mersch Pontus, Rademacher Jessica, Choi Hayoung, Lorent Natalie, Blasi Francesco, Vendrell Montserrat, Goeminne Pieter, Ringshausen Felix, De Soyza Anthony, Aliberti Stefano, Chalmers James D

Abstract excerpt

RATIONALE: The frequent exacerbator phenotype was previously defined using a threshold of ≥3 exacerbations per year in bronchiectasis. However, the contribution of each prior exacerbation to future risk as well as the influence of severe exacerbations and different etiologies and regions remain poorly understood. OBJECTIVES: To quantify the risk associated with each prior exacerbation of bronchiectasis in...

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PMID: 42348458
DOI: 10.1093/ajrccm/aamag297
PMCID: PMC13519352

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