Article
Empirical verification of evolutionary theories of aging.
Aging - 25 Oct 2016
Kyryakov Pavlo, Gomez-Perez Alejandra, Glebov Anastasia, Asbah Nimara, Bruno Luigi, Meunier Carolynne, Iouk Tatiana, Titorenko Vladimir I
Abstract excerpt
We recently selected 3 long-lived mutant strains of Saccharomyces cerevisiae by a lasting exposure to exogenous lithocholic acid. Each mutant strain can maintain the extended chronological lifespan after numerous passages in medium without lithocholic acid. In this study, we used these long-lived yeast mutants for empirical verification of evolutionary theories of aging. We provide evidence that the dominant...
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