Article
Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function.
Circulation. Cardiovascular genetics - 1 Dec 2016
Cossette Stephanie M, Bhute Vijesh J, Bao Xiaoping, Harmann Leanne M, Horswill Mark A, Sinha Indranil, Gastonguay Adam, Pooya Shabnam, Bordas Michelle, Kumar Suresh N, Mirza Shama P, Palecek Sean P, Strande Jennifer L, Ramchandran Ramani
Abstract excerpt
BACKGROUND: Cardiac metabolism is critical for the functioning of the heart, and disturbance in this homeostasis is likely to influence cardiac disorders or cardiomyopathy. Our laboratory has previously shown that SNRK (sucrose nonfermenting related kinase) enzyme, which belongs to the AMPK (adenosine monophosphate-activated kinase) family, was essential for cardiac metabolism in mammals. Snrk global homozygous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.