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Article

The AMPK-related kinase SNARK regulates muscle mass and myocyte survival

20 Dec 2015

Abstract excerpt

The maintenance of skeletal muscle mass is critical for sustaining health; however, the mechanisms responsible for muscle loss with aging and chronic diseases, such as diabetes and obesity, are poorly understood. We found that expression of a member of the AMPK-related kinase family, the SNF1-AMPK-related kinase (SNARK, also known as NUAK2), increased with muscle cell differentiation. SNARK expression increased...

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PMID: 26690705
DOI: 10.1172/jci79197

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