Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered postnatal maturation of striatal GABAergic interneurons in a phenotypic animal model of dystonia.

Experimental neurology - 1 Jan 2017

Bode Christoph, Richter Franziska, Spröte Christine, Brigadski Tanja, Bauer Anne, Fietz Simone, Fritschy Jean-Marc, Richter Angelika

Abstract excerpt

GABAergic disinhibition has been suggested to play a critical role in the pathophysiology of several basal ganglia disorders, including dystonia, a common movement disorder. Previous studies have shown a deficit of striatal GABAergic interneurons (IN) in the dtsz mutant hamster, one of the few phenotypic animal models of dystonia. However, mechanisms underlying this deficit are largely unknown. In the present...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dystonia
Share to Corpus Striatum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GABAergic Neurons

Share to Glutamate Decarboxylase

Share to Mesocricetus

Share to Parvalbumins

Share to Receptors, GABA-A

Share to Thyroid Nuclear Factor 1

Source

Identifiers

PMID: 27780732
DOI: 10.1016/j.expneurol.2016.10.013

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered postnatal maturation of striatal GABAergic interneurons in a phenotypic animal model of dystonia.PMID 27780732Read ↗

Deficit of striatal parvalbumin-reactive GABAergic interneurons and decreased basal ganglia output in a genetic rodent model of idiopathic paroxysmal dystonia.Semantic proximity Read ↗

Developmental profile of the aberrant dopamine D2 receptor response in striatal cholinergic interneurons in DYT1 dystonia.Semantic proximity Read ↗

Alterations in spontaneous single unit activity of striatal subdivisions during ontogenesis in mutant dystonic hamsters.Semantic proximity Read ↗

Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatumSemantic proximity Read ↗

Ketamine alters cortical integration of GABAergic interneurons and induces long-term sex-dependent impairments in transgenic Gad67-GFP miceSemantic proximity Read ↗

Selective dopamine D2 receptor deletion from Nkx6.2 expressing cells causes impaired cognitive, motivation and anxiety phenotypes in mice.Semantic proximity Read ↗

Postnatal Changes in K+/Cl- Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy.Semantic proximity Read ↗

Characterizing the phenotype of pre-Bötzinger Complex neurons in rats.Semantic proximity Read ↗

Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.Semantic proximity Read ↗

Development of the GABAergic phenotype in murine spinal cord-dorsal root ganglion cultures.Semantic proximity Read ↗

Vglut2 expression in dopamine neurons contributes to post-lesional striatal reinnervationSemantic proximity Read ↗

Development of subpopulations of GABAergic neurons in cat visual cortical areas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.