Article
Characterizing the phenotype of pre-Bötzinger Complex neurons in rats.
Neuroscience - 7 Jun 2025
Connelly Angela A, Bassi Jaspreet K, Voger Joshua J, Butler Andrew G, McDougall Stuart J, Allen Andrew M, Melo Mariana R
Abstract excerpt
The pre-Bötzinger Complex (preBötC) is a key medullary region responsible for generating breathing. In rodents, preBötC neurons are divided almost evenly between excitatory neurons, which express vesicular glutamate transporter 2 (VGluT2), and inhibitory neurons expressing either glutamic acid decarboxylase (GAD) or glycine transporter 2 (GlyT2). The interaction between excitatory and inhibitory neurons plays a...
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