Article
Pharmacogenomics in the clinic.
Nature - 15 Oct 2015
Relling Mary V, Evans William E
Abstract excerpt
After decades of discovery, inherited variations have been identified in approximately 20 genes that affect about 80 medications and are actionable in the clinic. And some somatically acquired genetic variants direct the choice of 'targeted' anticancer drugs for individual patients. Current efforts that focus on the processes required to appropriately act on pharmacogenomic variability in the clinic are moving...
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