Article
Functional variant of the P2X7 receptor gene is associated with human papillomavirus-16 positive cervical squamous cell carcinoma.
Oncotarget - 13 Dec 2016
Yang Yuh-Cheng, Chang Tzu-Yang, Chen Tze-Chien, Lin Wen-Shan, Chang Shih-Chuan, Lee Yann-Jinn
Abstract excerpt
Human papillomavirus (HPV) infection and the fate of HPV infected cervical epithelial cells are strictly associated with cervical cancer development. P2X7 receptor has been implicated in both the regulation of immune responses and apoptosis of cervical cancer cells. The study aims to investigate if polymorphisms in the P2RX7 gene are associated with the risk of cervical cancer in Taiwanese women. P2RX7 253 T/C,...
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