Article
ITPR3 gene haplotype is associated with cervical squamous cell carcinoma risk in Taiwanese women.
Oncotarget - 7 Feb 2017
Yang Yuh-Cheng, Chang Tzu-Yang, Chen Tze-Chien, Lin Wen-Shan, Chang Shih-Chuan, Lee Yann-Jinn
Abstract excerpt
Host immunogenetic background plays an important role in human papillomavirus (HPV) infection and cervical cancer development. Inositol 1,4,5-triphosphate receptor type 3 (ITPR3) is essential for both immune activation and cancer pathogenesis. We aim to investigate if ITPR3 genetic polymorphisms are associated with the risk of cervical cancer in Taiwanese women. ITPR3 rs3748079 A/G and rs2229634 C/T polymorphisms...
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